TY - JOUR AU - Ibrahim, Mohd Danial AU - Yunos, Yana Shaheera AU - Watanabe, Nobuo AU - Mohtadzar, Nur Alia Athirah AU - Semait, Siti Noor Haizum AU - Rigit, Andrew Ragai Henry AU - Sunami, Yuta AU - Kwang, Wong Lee AU - A. Rahman, Mohd Rahmat AU - Mohtar, Muhammad Zaidi PY - 2017/07/31 Y2 - 2024/03/29 TI - Micro-Needle with Polygonal Structure of Micro-Channel for Stress and Blood or Drug Flow Optimization JF - Engineering Journal JA - Eng. J. VL - 21 IS - 4 SE - DO - 10.4186/ej.2017.21.4.207 UR - https://engj.org/index.php/ej/article/view/1333 SP - 207-216 AB - <p>This paper presents micro-needle with different tip and inner structure of the needle for optimizations of pain stresses and drug or blood deliveries. The micro-needle comes with several design's parameters of length ranging from 5 mm to 50 mm and diameter ranging from 100 µm to 200 µm. A hollow micro-needle with four different tip designs which are 10°, D3-2, D6 and Quadruple are also designed to optimize the pain stresses parameters. In order to improve the flow deliveries, the inner structure of the channel is modified into various polygonal shape which is square, hexagon and dodecagon. It shows that, having less contact surface area between the skin and micro-needle's tip and polygonal shape of inner channel has better performance for both of the objectives. These feasible region of average velocity and stress of the micro-needle have satisfied in determining the best design for tip and inner channel of the micro-needle under certain conditions and constraints. The three-dimensional geometry study had improved the insertions performance and efficiencies in painless drug or blood deliveries.</p> ER -